PUBLICATIONS/PREPRINTS
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Since 2023 (Independent Lab) *Corresponding, Bolded = Chen lab members
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2018-2022 (Postdoc Research) *Co-first
11) M Wang, Z Chen*, Y Zhang (2022) CBP/p300 and HDAC activities regulate H3K27 acetylation dynamics and zygotic genome activation in mouse preimplantation embryos The EMBO Journal 41(22):e112012 Pubmed PDF
10) R Chen, Y Liu, MN Djekidel, W Chen, A Bhattacherjee, Z Chen, E Scolnick, Y Zhang (2022) Cell type–specific mechanism of Setd1a heterozygosity in schizophrenia pathogenesis Science Advances 8 (9), eabm1077 Pubmed PDF
9) Z Chen, Z Xie, Y Zhang (2021) DPPA2 and DPPA4 are dispensable for mouse zygotic genome activation and pre-implantation development Development 148 (24), dev200178 Pubmed PDF
8) Z Chen*, MN Djekidel*, Y Zhang (2021) Distinct dynamics and functions of H2AK119ub1 and H3K27me3 in mouse preimplantation embryos Nature Genetics 53 (4), 551-563 Pubmed PDF
7) Z Chen, Y Zhang (2020) Maternal H3K27me3-dependent autosomal and X chromosome imprinting Nature Reviews Genetics 21 (9), 555-571 Pubmed PDF
6) Z Chen, Y Zhang (2020) Role of mammalian DNA methyltransferases in development Annual Review of Biochemistry 89 (1), 135-158 Pubmed PDF
5) C Zhang*, Z Chen*, Q Yin, X Fu, Y Li, T Stopka, AI Skoultchi, Y Zhang (2020) The chromatin remodeler Snf2h is essential for oocyte meiotic cell cycle progression Genes & Development 34 (3-4), 166-178 Pubmed PDF
4) Z Chen, Q Yin, A Inoue, C Zhang, Y Zhang (2019) Allelic H3K27me3 to allelic DNA methylation switch maintains noncanonical imprinting in extraembryonic cells Science Advances 5 (12), eaay7246 Pubmed PDF
3) Z Chen, Y Zhang (2019) Loss of DUX causes minor defects in zygotic genome activation and is compatible with mouse development Nature Genetics 51 (6), 947-951 Pubmed PDF
2) W Zhang*, Z Chen*, Q Yin, D Zhang, C Racowsky, Y Zhang (2019) Maternal-biased H3K27me3 correlates with paternal-specific gene expression in the human morula Genes & Development 33 (7-8), 382-387 Pubmed PDF
1) A Inoue*, Z Chen*, Q Yin, Y Zhang (2018) Maternal Eed knockout causes loss of H3K27me3 imprinting and random X inactivation in the extraembryonic cells Genes & Development 32 (23-24), 1525-1536 Pubmed PDF
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2011-2017 (Graduate Reseach)
6) Z Chen, DE Hagen, T Ji, CG Elsik, RM Rivera (2017) Global misregulation of genes largely uncoupled to DNA methylome epimutations characterizes a congenital overgrowth syndrome Scientific Reports 7 (1), 1-14 Pubmed PDF
5) LG Siqueira, P Tribulo, Z Chen, AC Denicol, MS Ortega, VM Negrón-Pérez, J Kannampuzha-Francis, KG Pohler, RM Rivera, PJ Hansen (2017) Colony-stimulating factor 2 acts from days 5 to 7 of development to modify programming of the bovine conceptus at day 86 of gestation Biology of Reproduction 96 (4), 743-757 Pubmed PDF
4) Z Chen, DE Hagen, J Wang, CG Elsik, T Ji, LG Siqueira, PJ Hansen, RM Rivera (2016) Global assessment of imprinted gene expression in the bovine conceptus by next generation sequencing Epigenetics 11 (7), 501-516 Pubmed PDF
3) Z Chen, DE Hagen, CG Elsik, T Ji, CJ Morris, LE Moon, RM Rivera (2015) Characterization of global loss of imprinting in fetal overgrowth syndrome induced by assisted reproduction Proceedings of the National Academy of Sciences 112 (15), 4618-4623 Pubmed PDF
2) Z Chen, KM Robbins, KD Wells, RM Rivera (2013) Large offspring syndrome: a bovine model for the human loss-of-imprinting overgrowth syndrome Beckwith-Wiedemann Epigenetics 8 (6), 591-601 Pubmed PDF
1) KM Robbins, Z Chen, KD Wells, RM Rivera (2012) Expression of KCNQ1OT1, CDKN1C, H19, and PLAGL1 and the methylation patterns at the KvDMR1 and H19/IGF2 imprinting control regions is conserved between human and bovine Journal of Biomedical Science 19 (1), 1-10 Pubmed PDF