06/05/2025
We are thrilled to receive a 5-year NIH R01 award to support research on understanding the gene regulatory roles of long terminal repeat (LTR) retrotransposons in mouse early development using (epi)genome editing and multi-omics analyses.
05/28/2025
We contributed a protocol on chromatin analyses during Zygotic Genome Activation in mouse embryos. Cheers!
05/12/2025 Welcome Natalie Pfaltzgraff to our lab as a rotation student!
03/31/2025 ZY gave a talk in the weekly Developmental Biology divisional meeting on a new exciting story.
02/05/2025 ZY was honored to give a talk at the University of Missouri, Columbia! Proud to be a Mizzou alumni—Go Tigers!
01/24/25
Many things to celebrate this day!
Welcome Jin-Wen and Shoko!
Lauryn’s and Peiyao’s graduate school offers!
Lunar/Chinese New Year!
11/25/2024 Welcome Jin-Wen Kang (Ph.D) to our lab as a research fellow!
03/25/2024 Welcome Peiyao Liu to our lab! Our lab is really growing!
03/25/2024 Jian gave a very nice talk on his research in the weekly divisional meeting. Congratulations! Keep up the good work!
03/04/2024 Welcome Neha Gupta to our lab!
02/20/2024
Jian and Lauryn’s paper is online today! Congratulations!
01/31/2024 ZY gave a seminar titled “Decoding chromatin reprogramming and retrotransposon activation when life begins“ at the CCRF DB seminar series.
01/11/2024
Celebration of the first Chen lab paper “in principle“ acceptance! Cheers!
12/22/2023
Celebration of the holidays!
12/12/2023
We are excited to receive the Trustee Award ($200k over two years) from Cincinnati Children’s Research Foundation for studying retrotransposon function in mammalian early development.
10/11/2023 ZY gave a presentation titled “Systematic perturbation of thousands of retroviral LTRs“ at the CCHMC Regulatory Genomics Forum.
07/31/2023 Welcome Dr. Jian Yang to our lab!
06/05/2023 Welcome Lauryn Cook to our lab!! The Chen lab is growing!
05/19/2023 ZY gave a talk titled “Decoding epigenetic regulation in early development“ at the Division of Developmental Biology annual retreat.
01/03/2023
We successfully made the K99-to-R00 transition! The 3-year R00 award will support research to systemically dissect the mechanisms and functions of PcG proteins in mouse early development using the cutting-edge low-input chromatin profiling and rapid protein degradation techniques.
